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Two halves of Thanksgiving leftover sandwich on toasted white bread with cream cheese, cranberry sauce, sliced turkey, sausage stuffing, provolone cheese, lettuce and mayo.
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5 from 3 votes

Thanksgiving Sandwich (made with leftovers)

This Thanksgiving Sandwich is a delicious way to use up Turkey Day leftovers. All the best parts of the big meal piled onto a sweet and savory sandwich.
Prep Time10 minutes
Cook Time0 minutes
Total Time10 minutes
Course: Lunch
Cuisine: American
Keyword: Sandwich, thanksgiving
Servings: 1 sandwich
Calories: 552kcal
Author: Emily Walker

Ingredients

  • 2 slices Bread (white, brioche, ciabatta, sourdough, or dinner rolls)
  • 1 tablespoon cream cheese, softened
  • 2 tablespoons cranberry sauce
  • 2 slices turkey leftovers or deli turkey
  • ¼ cup stuffing
  • 1 slice provolone cheese
  • 1 leaf romaine lettuce
  • 1 tablespoon mayonnaise

Instructions

  • Toast bread and spread cream cheese on the bottom slice of bread.
    Two slices of toasted white bread with spread cream cheese on one slice.
  • Add cranberry on top of the cream cheese.
    Cranberry sauce on top of cream cheese spread on one slice of toasted white bread.
  • Top with turkey, stuffing, provolone, and lettuce. 
    Stuffing on top of turkey, cranberry sauce and cream cheese on a slice of toasted white bread.
  • Spread some mayonnaise on the top half of the bread, then sandwich it together!
    Thanksgiving leftover sandwich on two slices of toasted white bread with cream cheese, cranberry sauce, sliced turkey, sausage stuffing, provolone cheese, lettuce and mayo.

Video

Notes

  • Structure: Toast bread for extra support; keep cranberry over cream cheese to avoid sogginess.
  • Hot option: Warm turkey/stuffing first; press sandwich 2–3 minutes per side.
  • Substitutions: Use butter or goat cheese instead of cream cheese; swap provolone for white cheddar or Swiss.
  • Extras: Add mashed potatoes + gravy, tomato, red onion, or crisp bacon.
  • Storage: Best fresh; wrapped leftovers keep up to 1 day in the fridge.

Nutrition

Calories: 552kcal | Carbohydrates: 48g | Protein: 21g | Fat: 31g | Saturated Fat: 11g | Cholesterol: 63mg | Sodium: 909mg | Potassium: 202mg | Fiber: 3g | Sugar: 16g | Vitamin A: 598IU | Calcium: 372mg | Iron: 3mg